Our Chesterfield, MO hotel is conveniently located on I-64 just off exit 17 and only 23 miles west of downtown St. Louis.Business travelers will appreciate our hotel location near major companies such as St. Luke's Hospital, Pfizer, Crown Packaging, Instituform, Monsanto, Reinsurance Group of America and Amdocs. Staying at Holiday Inn Express Chesterfield will make it easier to visit popular area attractions like Six Flags St. Louis Amusement Park, Gateway Motorsports Park, Anheuser Busch Brewery, St. Louis Gateway Arch, St Louis Zoo, Splash City and Fairmont Horse Track.You’ll feel welcomed the moment you enter the lobby of the new Holiday Inn Express Chesterfield. We take pride in providing clean comfortable lodging and attentive service. Regardless of whether you’re staying at our hotel on business or pleasure, you can expect a warm and thoughtful staff dedicated to making you feel right at home.The Holiday Inn Express Chesterfield offers 91 well-appointed guest rooms. Additional hotel amenities include free high-speed, wireless Internet access, complimentary Suite Start breakfast bar daily, 24/7 Business Center and meeting space along with an indoor pool and fitness room featuring the latest equipment.